MYO15A and hearing loss disorder: The conservation and pathogenicity prediction study also strengthened our hypothesis that MYO15A pathogenic variants, c.5504G > A (p.R1835H) and c.10245_10247delCTC (p.S3417del), in the SB246 family and c.9790C > T (p.Q3264X) and c.10263C > G (p.I3421M), in the SB224 family were the causative pathogenic variants of hearing loss.