GALC and sphingolipidosis: We described proteopathic aggregations of fibrillized α-synuclein in central neurons of infantile and young adult patients affected by Krabbe’s disease (KD), a lysosomal sphingolipidosis caused by mutations in the galactosylceramidase (GALC) gene [8], describing for the first time a link between GALC metabolism and synucleinopathies [9].