In particular, RSF-1 overexpression (scores of 9+ to 12+).correlates with bigger tumor size (p = 0.0015), poor differentiation (p = 0.0097), nodal metastasis (p = 0.0001), and tumor stages (p < 0.0001) (Table 2 and Fig. 2A). This evidence concerns the gene RSF1 and neoplasm.