UTRN and Duchenne muscular dystrophy: Regenerating myofibers in both DMD and BMD patients show elevated levels of utrophin.82 In addition, some Duchenne patients have increased utrophin expression.83 Underscoring the ability of utrophin to partially compensate for dystrophin, such higher utrophin expression has been correlated with decreased disease severity.84 However, overall disease outcomes are unaffected, and symptoms in patients with higher levels of utrophin progress at only a delayed rate.