In another example, the coat protein (CP) and CP read-through protein of PLRV (polerovirus) are targeted to the nucleolus and although the implications of this from an infection perspective are unelucidated, it is known that nucleolar components such as fibrillarin are required for long-distance movement of PLRV and subsequent systemic plant infections (Haupt et al., 2005; Kim et al., 2007a). The gene discussed is CP; the disease is infection.