The database suggests increased overall mRNA synthesis for SOD1 and SOD2 in adenocarcinoma (142% and 77.1%, respectively), although the variations between patients are high as observed in adenoma development: SD 347.4 for SOD1 and SD 108.1 for SOD2. The metastatic disease shows a 515% increase in SOD1 expression and 73.2% increase in SOD2 expression; however, again, the SDs, SD 972.6 for SOD1 and SD 108.1 for SOD2, nullify the individual values. The gene discussed is SOD2; the disease is metastatic neoplasm.