Indeed, SOD3 was first identified as a therapeutic enzyme being able to inhibit efficiently liver damage in a paracetamol intoxication model, cardiovascular damage in a reperfusion model, and neointima growth in a restenosis model and only recently shown to promote unwanted growth in cancer models (39, 184, 189, 190, 192, 194, 195, 197, 332). The gene discussed is SOD3; the disease is cancer.