In the first study, hMLH1 and hMSH2 immunostaining was observed predominantly in the outer layer of tumor nests, whereas in the present study, variable staining was observed in both the outer/ameloblastic layer and stellate inner cells of tumoral nests, similarly to the second study, which also showed that MMRP are decreased in ameloblastomas in comparison with tooth germ, as we found in this study. The gene discussed is MSH2; the disease is ameloblastoma.