However, the hypomethylated DMRs were detected in genes with promoters occupied by the PML‐RARA fusion protein in acute promyelocytic leukemia (APL) cell lines, on the basis of Chip‐seq data 48, and in genes that form the macrophage‐enriched metabolic network (MEMN) and have a causal relationship with metabolic syndrome traits 11 (Supporting Information Table S3). Here, PML is linked to metabolic syndrome.