To further confirm the above findings, we searched the Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC) data collection for the clinical analysis, and revealed that CASC2 expression is down-regulated in the primary tumor, and more down-regulated in advanced stages (Fig.S4A-B and Supplementary Table 1). The gene discussed is CASC2; the disease is neoplasm.