TNFSF10 and neoplasm: The results showed that TRAIL treatment significantly suppressed tumor cell viability; the overexpression of miR-24 and miR-221 could promote tumor cell viability, and attenuate the suppressive effect of TRAIL on tumor cell viability; the inhibition of miR-24 and miR-221 could suppress tumor cell viability, and amplify the suppressive effect of TRAIL on tumor cell viability (Fig.S2A-B).