In SLE, there are raised levels of various autoantibodies, including ANA, anti-dsDNA, ENA, anti-Ro, anti-La, anti-RNP, and anti-Sm.35 ANA is most commonly used as a “screening” test, wherein a positive result will prompt testing of the other disease-associated antibodies. Here, BTG3 is linked to systemic lupus erythematosus.