Hence, PHPT1 and CDKN1A were significantly up-regulated at all time points in endometrial patients (Fig 6A and 6C, respectively) while a significant up-regulation in head and neck cancer patients was observed for PHPT1 and CDKN1A only at 48 hr, after the 2nd RT fraction (Fig 7A and 7C, respectively). The gene discussed is PHPT1; the disease is head and neck cancer.