Consistent with the results of R5 HIV infection, a similar lower susceptibility to X4 HIV (92/UG/029 strain) was also observed for ALVAC-induced CD4 T cells (mean p24+%: 1.82%) as compared to Ad5 vector-induced CD4 T cells (mean p24+%: 16.2%) (p<0.01) (Fig 1B). The gene discussed is CD4; the disease is HIV infectious disease.