Our data show that compared to Ad5 vector, ALVAC-induced T cells (CD4 and CD8) produce much higher levels of β-chemokines (MIP-1β) (Fig 5A); however, interestingly, neutralization of β-chemokines in ALVAC-stimulated PBMC only slightly increased HIV infection in ALVAC-specific CD4 T cells (Fig 5B), suggesting a modest role of β-chemokines in this process. The gene discussed is CD4; the disease is HIV infectious disease.