CD8A and Zika virus infectious disease: First predictions of ZIKV T cell antigens were conducted by modelling potential epitopes that could bind to different HLA class I or class II alleles, from the ZIKV proteome [86,87,88], and by identifying short peptides targeted by DENV-specific CD8+ T cells with conserved sequences between DENV and ZIKV [89], with the underlying assumption that these epitopes should stimulate cross-reactive T cells after sequential DENV and ZIKV infection.