Double‐hit or triple‐hit B‐cell lymphomas harboring concomitant chromosomal rearrangements involving c‐MYC and BCL2 and/or BCL6 genes with unfavorable prognoses have previously been included in DLBCL, but these are considered to be an independent disease subtype in the latest WHO classification updated in 2016 10. This evidence concerns the gene BCL2 and B-cell non-Hodgkin lymphoma.