MAP2K1 and melanoma: As a result, most of these target genes played roles in crucial cell function and pathways, including “protein‐binding, Pathways in cancer, Cell cycle, Melanoma, Proteoglycans in cancer, microRNAs in cancer, and so on.” Target genes involved in these top enriched pathways included fibrosis‐related genes (such as FGF9, FGF2, FGFR1, and FGFR3), immune‐related genes (such as TGFB2), tumor‐relevant genes (such as MAP2K1), and so forth.