The cause of the redistribution of ICa is also unknown, although the scaffolding protein caveolin 3 (Cav3) might play a role (Bryant et al., 2015; Bryant, Kong, Cannell, Orchard, & James, 2018), because it appears to localize ICa to the t‐tubules (Bryant et al., 2014) and undergoes downregulation in heart failure (Feiner et al., 2011; Fridolfsson & Patel, 2013). The gene discussed is CAV3; the disease is heart failure.