LOX and breast carcinoma: LOX is related to the poor prognosis in breast cancer (Chu et al., 2012), lung cancer (Liu et al., 2014), colorectal cancer (Nebuloni et al., 2016), uveal melanoma (Abourbih et al., 2010), pancreatic cancer (Miller et al., 2015), gastric cancer (Zhang et al., 2013), and laryngeal cancer (Lee et al., 2017).