According to the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in Atrial Fibrillation for Japanese (J-ROCKET AF) study, rivaroxaban 15 mg was as effective as warfarin in preventing ischemic stroke and systemic thromboembolism6. Here, F10 is linked to atrial fibrillation.