Next, we evaluated the expression of IL-12p35 and IL-12p40 by CD11c+ cells isolated from the spleen of L. donovani infected mice at various time points p.i. As shown in Fig. 5b, IL-12p35 expression was sustained over the course of infection in Hif1aflox/flox – Cd11c-Cre+ mice compared to the Cre− control group. Here, ITGAX is linked to infection.