The histological subtype results showed that increased AQP1 mRNA expression highly associated with unfavorable OS in patients of serous ovarian cancer, HR = 1.3 (1.12–1.52), P=0.00071 (Figure 3B), whereas expression level of AQP1 mRNA in endometrioid cancer patient did not show any correlation with OS, HR = 2.65 (0.3–23.7), P=0.37 (Figure 3C). Here, AQP1 is linked to ovarian serous adenocarcinoma.