Amongst the members of AQPs family, only AQP2 and AQP9 mRNA had no effect on the OS of ovarian cancers, i.e. AQP0, AQP1, and AQP4 mRNA expression were associated with poor OS, whereas high expression of AQP3, AQP5, AQP6, AQP8, AQP10, and AQP11 were associated with better OS for ovarian cancer patients. The gene discussed is AQP2; the disease is ovarian carcinoma.