Amongst the members of AQPs family, only AQP2 and AQP9 mRNA had no effect on the OS of ovarian cancers, i.e. AQP0, AQP1, and AQP4 mRNA expression were associated with poor OS, whereas high expression of AQP3, AQP5, AQP6, AQP8, AQP10, and AQP11 were associated with better OS for ovarian cancer patients. This evidence concerns the gene AQP3 and ovarian cancer.