For example, the lifetime QALYs gain was 0.42 for intravenous tPA treatment for acute ischaemic stroke within 4.5 hours,33 and 0.17 for clopidogrel for secondary prevention of stroke compared with aspirin.34 This may be due to the large magnitude of the effect of the mechanical thrombectomy (OR 2.046). Here, PLAT is linked to stroke disorder.