MAPT and Alzheimer disease: Also this model mimics key pathological characteristics of AD, such as tau hyperphosphorylation, neuronal cell loss, and impairment of hippocampus‐dependent memory, making this a relevant model to study the amyloid‐driven component of AD pathogenesis (Nitta et al, 1997; Brouillette et al, 2012; Cetin et al, 2013; Balducci & Forloni, 2014).