CD4 and tuberculosis: Guidelines from 2015 now recommend no less than 36 months for people without symptoms of active TB, irrespective of CD4 count, availability of TST, ART status or pregnancy.10–12 In high TB incidence, resource-constrained settings, absence of current cough, fever, night sweats and weight loss can be used as a screening tool for IPT eligibility.13–16 IPT provision should be supported by regular adherence support and monitoring, and ideally accompanied by pyridoxine to reduce the risk of symptomatic peripheral neuropathy.17