To further validate the effect of HBXIP on TAM resistance in vivo, we constructed different stable breast cancer cell lines including MCF-7-pCMV, MCF-7-HBXIP, BT474-pSilencer-Random, and BT474-pSilencer-HBXIP (Additional file 2: Figure S1i). Here, LAMTOR5 is linked to breast carcinoma.