Histone methyltransferase euchromatic histone lysine methyltransferase 2 (EHMT2), which suppresses the expression of fumarate hydratase in nasopharyngeal carcinoma [54], is recruited with enhancer of zeste homolog 2 (EZH2) by miR-584-3p in an Ago2-dependent manner to reduce matrix metalloproteinase 14 (MMP-14) expression in gastric cancer [55]. Here, MMP14 is linked to nasopharyngeal carcinoma.