Recently, Suwarto et al. [4] developed criteria for diagnosing pleural effusion and/or ascites as a marker of plasma leakage which involves four diagnostic variables: hemoconcentration≥15.1%, albumin concentration ≤ 3.49 mg/dL, platelet count ≤49,500/μL, and aspartate aminotransferase (AST) ratio ≥ 2.51. The gene discussed is ALB; the disease is Pleural effusion.