Increased expression levels were found for ADGRL2, ADGRL4, ADGRE1, ADGRE5, ADGRG2, and ADGRG6 in lupus nephritis and diabetic nephropathy, whereby ADGRL2, ADGRL4 and ADGRE5 were also upregulated in IgA nephropathy (Table 2). This evidence concerns the gene ADGRL4 and diabetic kidney disease.