Overall, the data obtained from the utilized databases indicate that almost all aGPCRs are associated to kidney diseases including APOL1-associated kidney disease, ccRCC, chRCC, CKD, diabetic nephropathy, focal segmental glomerulosclerosis (FSGS), hypertension-injured kidney, IgA nephropathy, lupus nephritis, minimal change disease, membranous glomerulopathy, pRCC, and vasculitis-injured kidney. Here, APOL1 is linked to kidney disorder.