VEGFA and familial pancreatic carcinoma: Pancreatic cancer results from dysregulation of oncogenes and tumor suppressor genes, as well as growth factors and their receptors, including epidermal growth factors, vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), and many cytokines, such as TGF-β, IL-1, IL-6, TNF-α, and IL-8, which modulate pathways involved in growth and differentiation [124, 125].