While there is no direct evidence to suggest the involvement of the hCAP-D2 subunit in human cancers, it is worthwhile to note that there is emerging evidence to suggest that hCAP-D2 can indeed interact with other two non-SMC subunits of condensin I, hCAP-G and hCAP-H, the abnormal expression of which are both identified as biomarkers for cancers and reported as potential targets for therapeutic treatments for cancers [90, 92]. The gene discussed is NCAPG; the disease is cancer.