The differences between parental strains and CcS/Dem strain CcS-20 persist after L. major infection, whereas the differences between expression of parents and CcS-5 and CcS-16 and between parent B10 and the strain B10.O20 disappear after infection (Figure 1A; Figure S1A in Supplementary Material; Tables 1A,B). Here, CCS is linked to infection.