216, P < 0.001), tumor size 5–10 cm (HR = 0.640, P = 0.004), BCLC stage A (HR = 0.287, P < 0.001), antiviral therapy (ART) before HBV-related HCC diagnosis (HR = 0.443, P < 0.001), ART after HBV-elated HCC diagnosis (HR = 0.529, P < 0.001), and AFP < 400 ng/ml (HR = 0.570, P < 0.001) were related to better overall survival rate. This evidence concerns the gene AFP and neoplasm.