PLA2G7 and coronary artery disorder: Secretory phospholipase A2 (sPLA2) and lipoprotein-associated phospholipase A2 (Lp-PLA2) were identified in animal and observational studies in humans, as potential risk factors for coronary heart disease due to their putative effects on lipids and inflammation (Rosenson et al., 2010; Wang et al., 2011).