P70S6K plays an oncogenic role in the malignant behavior of tumors, for example, in non-small cell lung cancer (In et al., 2016; Qiu et al., 2016), breast cancer (Esteva et al., 2010), pancreatic cancer (Chai et al., 2015), acute lymphoblastic leukemia (Li H. et al., 2015), ovarian cancer (Ataie-Kachoie et al., 2015) and glioma (Zhang et al., 2015). Here, RPS6KB1 is linked to acute lymphoblastic leukemia.