MAPT and semantic dementia: The fact that Frontotemporal dementia with Parkinsonism linked to Chromosome 17 (FTDP-17), a tauopathy, is caused by the mutation of the tau gene MAPT indicates that tau may be a causative factor for other tauopathies in addition to FTDP-17 (Hutton et al., 1998; Poorkaj et al., 1998; Spillantini et al., 1998).