If the TAp73/deltaNp73 isoform ratio is increased by miR-193a-5p in PCa cells, the expression levels of MDM2 and P21 (CDKN1A) might be elevated, and TP73 might function as a tumor suppressor, leading to the reduced effect of the CCND1/CDK4 complex and G1 arrest. This evidence concerns the gene MDM2 and posterior cortical atrophy.