TAOK2 and Anxiety: We assessed novelty-induced exploration and anxiety in the open field test, where Taok2 KO mice traveled longer distances (effect of genotype: F2, 77 = 12.89; p < 0.001) and further away from the walls (effect of genotype: F2, 77 = 8.38; p < 0.001, Figs 2a, b) during the 30-min trial, with increased time spent in the center and decreased time spent in the border (Supplementary Fig. 4c, d).