In fact, TAT-GST-L-GILZ fusion protein inhibited cellular proliferation in an anaplastic thyroid cell line and when inoculated into mice that had been subcutaneously injected with anaplastic thyroid cancer cells, the size and weight of the tumor was reduced (Fig. 6). The gene discussed is TSC22D3; the disease is thyroid gland undifferentiated (anaplastic) carcinoma.