Polyunsaturated fatty acids (PUFAs), such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have a cardioprotective effect by reducing proinflammatory gene expression (TNF-alpha and IL-1ß [9, 10]), and by increasing gene expression of adiponectin [11, 12], which is protective against vascular dysfunction and insulin resistance [13, 14]. Here, ADIPOQ is linked to Insulin resistance.