TNF and neoplasm: So we can conclude that Lactobacillus acidophilus DSMZ 20079 cell-free pentasaccharide enhances immune function, particularly that of cytotoxic T lymphocytes (CD8+ T cells) and through the inhibition of TNF, IL2 and IL8 cell-signalling pathways by our treatment could be another factor that suppresses the NF-κB pathway and subsequently, prevent tumor cells proliferation.