The human BRIP1 gene (also named FANCJ or BACH1) is located on chromosome 17q22, comprising of 19 introns and 20 exons, and encodes BRCA1-associated C-terminal helicase 1 [1,4] And its mutations that affect helicase activity have been identified in patients suffering early-stage breast cancer. Here, BRIP1 is linked to breast carcinoma.