CD8A and eosinophilic esophagitis: A genome-wide RNA sequencing analysis showed that lncRNAs show differential expression in CD8 T cells;[20] lncRNAs might be acting as enhancer elements during T-helper cell differentiation.[21] The lncRNA BANCR is known to be upregulated in eosinophilic esophagitis, which is another allergic inflammatory disorder, and is induced in IL-13 in primary esophageal epithelial cells.[22]