MOG and optic neuritis: Again, there are striking similarities in plaque distribution between MOG-abspositive patients and corresponding MOG-sensitized Brown Norway (BN) or Dark Agouti (DA) rats: Also in these animals, simultaneous lesions in both spinal cord and optic nerve, and bilateral loss of myelin from the optic nerves were seen, and there were cases with optic neuritis or with myelitis only [48].