CRP and obesity due to melanocortin 4 receptor deficiency: Age (HR = 1.036 95% CI 1.020 to 1.053) and CRP levels (HR = 1.123 95% CI 1.077 to 1.171) were a significant risk factor for mortality while obesity (HR = 0.499 95% CI 0.305 to 0.817) showed a protective effect.