Supplementary Table 3 shows all the results obtained from the three different target enrichment analysis performed. Figure 6 shows as 7 key members (NUMB, DTX4, DTX3L, PSEN1, APH1A, ADAM17 and EP300) of that pathway are predicted as miRComb miR-148a targets in our pancreatic cancer samples. This evidence concerns the gene DTX3L and familial pancreatic carcinoma.