Among them, HDAC1, HDAC3, and LSD1 were barely expressed in hiPSCs and normal somatic cells (fibroblasts and T-lymphocytes), but they were strongly expressed in hiPSC-derived teratomas and cancer cell lines (K562, HeLa and HEK293) at the protein level (Figure 1A and Supplementary Figure 1). The gene discussed is HDAC3; the disease is cancer.