MYCN and neoplasm: Accordingly each tumor was determined to have either MYCN protein overexpression [MYCN protein (+)] or MYCN protein negative/weak expression [MYCN protein (−)/(+/−)] (Figures 1E, 1F, and 1G) and either MYC protein overexpression [MYC protein (+)] or MYC protein negative/weak expression [MYC protein (−)/(+/−)] (Figures 1H, 1I, and 1J).