Since p62-mediated selective autophagy plays a crucial role in DNA repair in cancer cells [22, 23, 27], we believe that LIMD1 protects EBV-transformed cells from DNA damage by playing an indispensable role in induction of p62-mediated selective autophagy, which serves as a survival mechanism by participating in DNA repair in cancer cells that are usually deficient in traditional DNA repair mechanisms such as non-homologous end jointing (NHEJ) [14, 23]. The gene discussed is SQSTM1; the disease is cancer.