They reported CRC-specific previous associations between miR-101 and miR-320 and β-catenin, miR-224 and GSK3β, and miR-490-3p and FRAT1. We did not see any of these associations, however we only examined miRNA associations with genes that had a more meaningful FC and since we were examining multiple genes and miRNAs, our correction for multiple comparisons was greater. This evidence concerns the gene FRAT1 and colorectal carcinoma.