In a study of immune function of patients with SLE [15], NEAT1 expression was increased in the PBMCs of these patients; NEAT1 expression increases rapidly in PBMCs by stimulation with LPS in vitro, and peak levels are reached at 2 h, compared with 12–48 h required for PCT to reach peak levels [29]. This evidence concerns the gene NEAT1 and systemic lupus erythematosus.