CD38 and B-cell chronic lymphocytic leukemia: Using the Binet staging classification, 50 CLL patients (56.8%) were at stage A, 16 (18.2%) at stage B, and 22 (25.0%) at stage C. Positive CD38 expression was encountered in 15 (17.0%) cases, while 73 (83.0%) patients had CD38-negative leukemic B cells.